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High Definition video (HD) Aymen Attou is a PhD student in the laboratory of Prof. Gero Wedemann (Institute for Applied Computer Science, University for Applied Sciences Stralsund, Stralsund, Germany). At the "Nuclear architecture & Function" symposium in Toulouse, he presented his work "Effects of CTCF and Cohesin complexes on chromatin ...

https://www.ibiology.org/cell-biology/cohesin The cohesin protein complex joins sister chromatids together before they are segregated during mitosis. In this talk, Dr. Peters presents evidence that cohesin also plays an important role in DNA folding and genome organization. Talk Overview: It has been known for many years that the protein ...

https://www.ibiology.org/cell-biology/cohesin The cohesin protein complex joins sister chromatids together before they are segregated during mitosis. In this talk, Dr. Peters presents evidence that cohesin also plays an important role in DNA folding and genome organization. Talk Overview: It has been known for many years that the protein ...

### Keywords ### #CTCFloops #nuclearcompartments #chromatinorganization #importantcomponents #CTCF #compartments #loops #RTCLTV ### Article Attribution ### Title: Chromatin alternates between A and B compartments at kilobase scale for subgenic organization Authors: Hannah L. Harris, Huiya Gu, Moshe Olshansky, Ailun Wang, Irene Farabella, Yossi ...

Hi-C | chromosome conformation capture | 3D chromatin architecture For Notes, flashcards, daily quizzes, and practice questions follow Instagram page: https://www.instagram.com/animatedbiologywitharpan/ Facebook page: https://www.facebook.com/Animated-biology-with-Arpan-109894017509038/?ref=pages_you_manage Follow me on other social media ...

Abstract A fundamental challenge in studying cell function and disease is understanding how cis-regulatory regions control gene expression. Sequences of these regions specify the binding sites of multiple transcription factors, and understanding regulatory function requires the understanding of how multiple transcription factors bind ...

Presented By: Andrea Johnstone, Ph.D. & Lori Euler Speaker Biography: Andrea Johnstone, Ph.D. is the Senior Director of Product Development at EpiCypher, a pioneer of innovative research solutions to advance chromatin science. Andrea earned her Ph.D. in Neuroscience at the University of Miami Miller School of Medicine. At EpiCypher, she applies ...

A video demonstrating chromosome organization by loop extrusion with barrier elements. The loop extrusion is done by cohesin and oriented barriers can be established by CTCF. More info: "Emerging Evidence for Loop Extrusion" Geoffrey Fudenberg*, Nezar Abdennur*, Maxim Imakaev, Anton Goloborodko, and Leonid Mirny, MIT (Feb, 2018). https://www ...

This video explains how histone chaperones and chromatin remodeling complexes are essential for efficient nucleosome assembly. Micrococcal nuclease assay used by researchers in 2005 to decipher the roles of chromatin remodeling is also discussed in this video. #csirnet #csirnetexam #gateexam #biology #lifescience #dna #chromatin #research

This video explains the structure of chromatin fiber, highlighting the roles of structural proteins and histones in DNA packaging within the cell nucleus. It details the formation of nucleosomes and the involvement of histone H1 in chromatin compaction. View this video (and more like it) on LabXchange: https://www.labxchange.org/library/items ...

In this free webinar, Dr. Michael Garbati, Technical Support Scientist at Active Motif will cover in depth, the popular technique of ATAC-Seq and how it is used to generate profiles of accessible, or open chromatin regions within the genome, as well as discuss the application of the data in epigenetics research. ATAC-Seq is a powerful technique ...

Scientific Reports - Super-resolution visualization of chromatin loop folding in human lymphoblastoid cells using interferometric photoactivated localization microscopy

Keywords: Genome, chromosome, chromatin, 3D Genome, Epigenetics Synopsis: This video recapitulates our current understanding of genome organization in the three-dimensional space of the cell nucleus, starting from nucleosomes, which wrap 146 base pairs of DNA, all the way to entire chromosome territories that may contain hundreds of million ...

This animation explains epigenetics, the study of changes in the pattern of gene expression that is regulated independently of the DNA sequence itself, and depends on modifications and conformational changes of the chromatin, the basic unit of our chromosomes. Epigenetics is central to our understanding of the role the environment plays and how ...

️ 🏃🏽‍♀️ℹ️ Learn more about the benefits of the CUT&RUN assay: https://cst-science.com/cutandrun CUT&RUN is a low cell number alternative to chromatin immunoprecipitation. This animation describes how specific protein-DNA complexes are isolated to enable chromatin mapping. Transcript: Dynamic interactions between proteins and ...

In this episode of the Epigenetics Podcast, we talked with Viviana Risca from Rockefeller University about her work on RICC-Seq and how it's used to probe DNA-DNA contacts in intact or fixed cells using ionizing radiation. This Interview covers Dr. Viviana Risca's cutting-edge methodologies, such as RICC-seq, which enables high-resolution ...

Suhas Rao and Miriam Huntley (of the Aiden Lab) describe a 3D map of the human genome at kilobase resolution, revealing the principles of chromatin looping. Guest Origami Folding: Sarah Nyquist. Suhas S.P. Rao*, Miriam H. Huntley*, Neva C. Durand, Elena K. Stamenova, Ivan D. Bochkov, James T. Robinson, Adrian L. Sanborn, Ido Machol, Arina D ...

#csirnetlifescience #gatebiotechnology #lifesciences #cuetpg Learn all about Chromatin and Chromosome in this educational video by Pranav Kumar. Perfect for those preparing for CSIR NET Life Sciences, GATE, CUET PG, or IIT JAM exams. TELEGRAM https://t.me/CSIR_NET_Life_Sciences_GATE_BT INSTAGRAM https://www.instagram.com/pathfinderacademy ...

Created by Tracy Kim Kovach. Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/biomolecules/gene-control/v/regulation-of-transcription?utm_source=YT&utm_medium=Desc&utm_campaign=mcat Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/biomolecules/gene-control/v/jacob-monod-the-lac-operon?utm_source=YT&utm ...

During plenary 1 of our North American Cystic Fibrosis Conference, the speakers explore different approaches to overcoming the biological obstacles and unique clinical trial challenges for developing cystic fibrosis genetic therapies. Daniel Siegwart, PhD, from the University of Texas Southwestern Medical Center, discusses how scientists are ...

Chromatin Structure and Function | CUET-PG | CUET-PG EXAM 2024 | Bansal Academy 🌟 Unravel the Mysteries of Chromatin Structure and Function! CUET-PG Exam 2024 Coaching by Bansal Academy! 🌟 Calling all aspiring CUET-PG examinees! Are you ready to delve into the intricate world of Chromatin Structure and Function? Look no further! Bansal ...

CUT&Tag (Cleavage Under Targets and Tagmentation) is a novel chromatin profiling technique that utilizes pAG-Tn5, a primary antibody, and a secondary antibody to unravel protein-DNA interactions across the genome. Unlike ChIP-seq, CUT&Tag does not rely on immunoprecipitation, requiring significantly fewer cells or tissue per individual assay ...

This video lecture describes 1. What is chromatin ? 2. What is chromatin immunoprecipitation? 3. When and why Chromatin immunoprecipitation is performed? 4. What are the different steps involved in Chromatin Immunoprecipitation (ChIP) ? 5. How ChIP analysis is performed ? 6. What is Chromatin Immunoprecipitation protocol? Biology Lectures is a ...

During development, epigenetic heterogeneity gives rise to different cell types with different functions. By stably instructing the activation and deactivation of genomic loci to catalyze specific signaling cascades, epigenetic mechanisms play a pivotal role in lineage commitment and cellular differentiation. What remains elusive, however, is ...

Chromosome conformation capture techniques are a set of molecular biology approaches used to analyze the spatial organization of chromatin and interaction of genomic regions in a cell. The methods basically measure intractions between genomic loci. Its also famous with the name 3C. 3C based technologies include. 3C classic, 4C, 5C, Hi-C The set ...

ChIP is a very powerful technique that allows the localization of proteins on DNA regions in the genome. This webinar gives an introduction to the technqiue, as well as protocols and troubleshooting tips. Watch the full video at: http://www.abcam.com/IntroToChIP12YT

If you are new to chromatin biology and epigenomics, you have come to the right place! In this part of our Chromatin Mapping Basics series, EpiCypher gives a basic introduction to chromatin structure and how it regulates gene expression. We explain the functions of histone post-translational modifications and other chromatin-associated proteins ...

This video animation shows how gene editing might one day be used to edit mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene that cause cystic fibrosis. This is one potential option for a cure to CF. Learn more about gene editing in CF: https://www.cff.org/Research/Research-Into-the-Disease/Restore-CFTR-Function ...

explorebiology.org/bio-dictionary Chromatin is a complex of DNA and protein, found in eukaryotic cells, which packages DNA molecules into compact structures to fit within cells. Chromatin also regulates gene expression, controlling which genes are expressed when and where in the body, helps chromosomes correctly segregate into daughter cells ...

Brief introduction to epigenetic regulation including the the two states of chromatin: euchromatin and heterochromatin. Transcript Epigenetic regulation encompasses a number of different modifications to chromatin. These include methylation of the DNA on cytosine bases, a modification that can further be oxidized, as well as modification of the ...

Chromatin Immunoprecipitation (chip assay)- This lecture explains about the chromatin immunoprecipitation technique also known as Chip assay. it involves the antigen antibody reaction to precipitate chromatin structure. Chip assay principle and mechanism is well explained along with the importance of the chromatin immunoprecipitation assay. For ...

Richter’s transformation is a rare and very aggressive complication of chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), where the disease turns into a much more aggressive lymphoma, usually diffuse large B cell lymphoma (DLBCL). Haemopoietic (blood forming) stem cell transplants (HSCT) are one of the only successful ...

Jan Lammerding - Investigating Rapid Nuclear Mechanotransduction by Mapping Genome-wide Changes in Transcription and Chromatin Accessibility Mounting evidence suggests that the nucleus plays a crucial part in cellular mechanotransduction to initiate cellular functions like differentiation or stress response. It is not yet known, however, if ...

Thank you for watching this lecture. Hope this lecture was helpful. Keep Supporting , don't forget to subscribe and share. CELL SIGNALING https://youtube.com/playlist?list=PLpjejUZhokbMWN0_egYHnp_6GrTuai8tZ CSIR NET PREPARATION STRATEGY https://youtube.com/playlist?list=PLpjejUZhokbMLIrYiu6m8LESza_VkLYRB UNIT WISE STRATEGY https://youtube.com ...

The SWI/SNF chromatin remodeling complex is a protein complex that plays a crucial role in modifying chromatin structure to regulate gene expression. "SWI/SNF" stands for Switch/Sucrose Non-Fermentable, referring to the yeast genes where this complex was first identified. This complex uses the energy from ATP hydrolysis to reposition, eject, or ...

Chromatin-Con: 2021 Epigenetic Mechanisms & Human Disease Meeting Diana Hargreaves, Ph.D. Associate Professor in the Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies San Diego, USA Presents: Remodeling the Chromatin Landscape: SWI/SNF Complexes in Development and Disease

The 3D organization of our genome plays a crucial role in development, aging, and disease, but what controls this complex spatial folding of DNA remains largely mysterious. In this video, Dr. Steven Wang and Yubao Chen of Yale University unveil a groundbreaking platform called Perturb-tracing that enables large-scale discovery of chromatin ...

A brief, simplified explanation of Chromatin Immunoprecipitation, a technique used to determine binding sites of DNA-associated proteins. I MADE A MISTAKE IN THE EXPLANATION! The video states that cells are lysed first, followed by cross-linking. The order is actually the other way around. A cross-linking agent is used first to fix the proteins ...

In this step-by-step guide to ChIP webinar, we introduce this powerful technique and provide guidance on selecting antibodies and troubleshooting. Watch the full video at:http://www.abcam.com/ChIPstepbystep14YT

Click on the CC button to get captions in other languages! In the chromatin immunoprecipitation visual protocol video, you will learn to crosslink protein DNA, prepare cells for shearing, shear chromatin for ChIP, analyze DNA fragment sizes, precipitate your DNA-protein of interest, and load your DNA for amplification and detection. Full length ...

Hey Friends, ATAC sequencing is used to map chromatin accessibility genome wide. ATAC seq uses hyperactive Tn5 Transposase, an enzyme which inserts short adaptor sequences in open chromatin regions. Sequencing is done by Next Gen Sequencing. An Introduction to Next Gen Sequencing: https://youtu.be/CZeN-IgjYCo References: https://www.ncbi.nlm ...

This video describes the basic concepts and use of chromatin immunoprecipitation in a concise manner and also describes how this technique is used to detect DNA protein interaction in Vivo.

Presented By: Fatima Valdes Mora, Ph.D. & Xiaoti Guo, Ph.D. Webinar: Deciphering Cancer Cell Heterogeneity for Precision Medicine Webinar Abstract: Single-cell ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing, scATAC-seq) is a relatively new and powerful technique that allows researchers to identify open chromatin regions ...

Introduction to assays for chromatin accessibility (ATAC-seq, MNase-seq, DNase-seq), brief intro to single cell ATAC-seq. MCB 182: Introduction to Genomics lecture videos Course playlist: https://www.youtube.com/playlist?list=PLpzXFzEHUCQdveBWm63MbUdGK_t0Nt23F

This video talks about the Chromosome structure, Chromatin organization, 3D chromatin and levels of organization in chromosomes. Video links: ATAC seq: https://www.youtube.com/watch?v=QwsWhFHH5jE&t=4s ChIP seq: https://www.youtube.com/watch?v=7_-Or4ARyH0&t=22s For Notes, flashcards, daily quizzes, and practice questions follow Instagram page ...

This module discusses the ways that we study histone modifications in epigenomes, primarily through chromatin immunoprecipitation (ChIP) and ChIP-Seq analysis. At the beginning of this course module you will be introduced to the basics of ChIP and ChIP-Seq analysis followed by a more practical section on how to prepare for ChIP and how to ...