mavii

Scientists theorized that Toll-like receptors (TLRs ... It is, therefore, an example of Janeway's PAMPs. In addition, Poltorak et al. (1998) demonstrated that mice with a defective version ...

C) Signal transduction. The ligand binds to a site in the extracellular domain of the receptor (not shown) and induces a conformational change that activates the cytoplasmic domains, enabling ...