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However, common diseases, such as type 2 diabetes and many ... genetic variations on disease risk 2. Acting on the score Several companies claim that they can calculate PRSs for multiple disorders ...

Longitudinal association of cumulative risk factors in early life, genetic risk, and healthy lifestyles during adulthood with the risk of type 2 diabetes 1. In this prospective cohort study, a higher early-life risk factor score (ERS) was associated with a dose-dependent increased risk of developing type 2 diabetes (T2D) later in life.